Because discovery is such a big part of the appeal, many players prefer lobbies that categorize games by theme, volatility, and features like expanding wilds, buybonus functionality, or cluster pays
The infect strategy, while not having direct support since Phyrexia: All Will Be One, has still been improved thanks to additional cards that care about counters
Sideboard and Answers: While sideboards are to be tailored to any given player's meta the above cards listed might help when dealing with the earlier described bad match-ups
Every card destroyed, lost, or damaged permanently reduces available supply, while demand is structurally supported by a growing global collector community
Settup (Ramp & Color Fixing) To talk about the setup a bit more having a mana Sliver (Manaweft Sliver, Gemhide Sliver, or Cryptolith Rite) is essential