Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) mal-acetyl-dap-m-PEG4 37 SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCC#C)[C@@]1([H])NC(=O)N2 Purity (HPLC):

37 SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCC#C)[C@@]1([H])NC(=O)N2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

improving its performance in labeling applications

96 SMILES ClCCOCCOCCOCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

NCCOCCOCCOCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) mal-acetyl-dap-m-PEG4 37 SMILES: [H][C@]12CS[C@@H](CCCCC(=O)NCC#C)[C@@]1([H])NC(=O)N2 Purity (HPLC):SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through