Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand 77 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCC#C Purity (HPLC):

77 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCC#C Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

442 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C19H31N5O7 Molecular Weight 441

BCN reacts efficiently with azides to form stable 1

31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand 77 SMILES: [O-]S(=O)(=O)C1=CC(=CC=C1C1=C2C=C3CCC[N+]4=C3C(CCC4)=C2OC2=C3CCCN4CCCC(C=C12)=C34)S(=O)(=O)NCC#C Purity (HPLC):SOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine