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It has the spectral properties identical to those of other ROX conjugates
Product Name CA-amide-PEG3-Biotin Synonyms biotin Halotag Ligand PEG3 CAS Number N/A Related CAS N/A Molecular Formula C29H53ClN4O8S Molecular Weight 653
146 SMILES BrC1=CC=C2CN(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader
Product Name DOTA-tris(t-Bu)ester-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C36H68N8O10 Molecular Weight 772
Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan aniline It has the spectral propertiesSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage
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