Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan biotin SB-715992 CAS Number 336113-53-2 Related

SB-715992 CAS Number 336113-53-2 Related CAS Molecular Formula C30H33ClN4O2 Molecular Weight 517

Product Name Pomalidomide-5'-PEG5-OH Synonyms CAS Number 2641838-56-2 Related CAS Molecular Formula C23H31N3O9 Molecular Weight 493

137 Purity (HPLC) >= 95% Solubility DMSO

Product Name DBCO-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C68H101N7O20 Molecular Weight 1336

NCCOCCOCCOCCOCCOCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-Exatecan biotin SB-715992 CAS Number 336113-53-2 RelatedSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker