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CC0651 is an E2 enzyme inhibitor
Product Name Mal-Lys(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Synonyms CAS Number Related CAS Molecular Formula C93H153N11O28 Molecular Weight 1873
Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C50H71N7O20 Molecular Weight 1090
When used in applications like protein labeling
such as MRI contrast agents
MC-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE fluorescent CC0651 is an E2 enzymeSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers
