Lenalidomide-5'-CO-C3-alkyne amine-amine 1038/s41589-020-0594-x

1038/s41589-020-0594-x

Product Name Pomalidomide-C4-amine HCl Synonyms Pomalidomide-4'-C4-amine HCl CAS Number 2162120-73-0 Related CAS 1957236-34-8 (free base) Molecular Formula C17H21ClN4O4 Molecular Weight 380

35 SMILES COC1=C(OC)C=C2CN(CC2=C1)C(=O)C1=C(SC2=C(Cl)C=CC=C2Cl)C=C(NC1=O)C(F)(F)F Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

79 SMILES: CC1(C)\C(=C/C=C/C2=[N+](CCCCCC(=O)OCC#C)C3=CC=CC=C3C2(C)C)N(CCCS([O-])(=O)=O)C2=CC=CC=C12 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

352 SMILES OCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Lenalidomide-5'-CO-C3-alkyne amine-amine 1038/s41589-020-0594-xDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Lenalidomide 5' CO C3 alkyne Synonyms CAS Number n a Related CAS Molecular Formula C19H19N3O4 Molecular Weight 353. 378 SMILES O=C(CCCC#C)NC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room