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Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C93H155N13O31 Molecular Weight 1951
Indisulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase
4 Purity (HPLC) >= 95% Solubility DMSO
Product Name Thalidomide-5'-O-PEG3-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H25N5O8 Molecular Weight 475
189 Purity (HPLC) >= 95% Solubility DMSO
Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-Exatecan Size:5mg Product Name Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I
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