DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP halide allowing the non-internalized probe to

allowing the non-internalized probe to be released from the cell surface using the reducing agent sodium 2-mercaptoethanesulfonate (MESNA)

Product Name DOTA-C5-azide Synonyms CAS Number n/a Related CAS Molecular Formula C21H38N8O7 Molecular Weight 514

64 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Azide-Propionyl-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C43H65N9O15 Molecular Weight 948

5-dimethoxybenzaldehyde Synonyms CAS Number n/a Related CAS Molecular Formula C10H12O4 Molecular Weight 199

DBCO-Hexanoyl-Gly-Gly-Phe-Gly-PAB(m-PEG8)-PNP halide allowing the non-internalized probe toSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,