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Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg DBCO has been extensively used

SKU: 38522724014

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Description

DBCO has been extensively used in copper-free click chemistry

Product Name DOTA-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C25H39N7O10 Molecular Weight 597

A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy

Product Name MC-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C50H73N7O17 Molecular Weight 1044

S)-AHPC-CO-PEG5-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C36H52N4O9S Molecular Weight 716

Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg DBCO has been extensively usedSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage

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