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Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP snap 031 Purity (HPLC) >= 95%

SKU: 28596094833

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Description

031 Purity (HPLC) >= 95% Solubility DMSO

Product Name Thalidomide-C3-PEG1-OH Synonyms Thalidomide-4'-C3-PEG1-OH CAS Number 2416133-06-5 Related CAS Molecular Formula C18H20N2O6 Molecular Weight 360

1 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCCl)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

34 SMILES OC(=O)C(F)(F)F

Ready for conjugation to a target protein ligand to form PROTACs containing Lenalidomide as cereblon ligand

Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP snap 031 Purity (HPLC) >= 95%SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating

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