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Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg where multiple targets can be

SKU: 27329489345

4.1
USD495.00 USD517.00

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Description

where multiple targets can be visualized simultaneously

and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators

When the probe binds to its cellular targets

701 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC(=CC=C2C([O-])=O)C(=O)NCCOCCOCCOCCN=[N]#N)=[N+](C)C)=C1

Product Name: 5-FAM Synonyms: 5-Carboxyfluorescein CAS Number: 76823-03-5 Molecular Formula: C21H12O7 Molecular Weight: 376

Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg where multiple targets can beSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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