I'm sure you recognize this crazy card: While it's not quite the same as removing all of the combo pieces from a deck, for some decks getting rid of all of the Emrakuls can destroy their primary strategy and may very well be worth it
Many decks tried to smooth out their mana curves in order to try and make Void less devastating, but there always seemed to be a good number to choose, and the existence of quality bounce spells Repulse and Recoil meant you often had a decent read on their hand even if you hadn't looked at it directly and also made it much easier to leave them with multiple cards in the same casting cost and not take damage while building up to five
The Best Black Cards In Phyrexia: All Will Be One Phyrexia Has Even Further Horrors For Us To Meet Ive been playing a lot of Mono-Black Devotion in Explorer lately, so Im particularly excited about the new cards in this color
While the fact that it self-destructs is a concern, it might be similar to "Loyal Apprentice" in terms of usability, as you can cast Tymna the turn after it lands and attack immediately
So, casting it means game over